1429
- It was at the Château de Chinon that Joan of Arc met the Dauphin of France, who accepted her services on March 22. She then travels to Blois, from where a supply convoy leaves for Orléans at the end of April. Before her departure, Joan of Arc was blessed in the château chapel.

1465
- To punish Pierre d'Amboise for rallying to the League of the Public Good - a revolt against royal rule - Louis XI had his fortress at Chaumont razed to the ground. Four years later, he pardoned Pierre and even provided part of the funds needed to rebuild the château.

1519
- Work begins on Chambord and Leonardo da Vinci dies in Amboise.

1534
- On the night of October 17-18, Protestants posted anti-Mass leaflets in several towns across the kingdom, including on the door of Francis I's bedroom at the Château Royal in Amboise. The leaflet affair marked the beginning of the crackdown on Protestantism.

1560
- The deed of transfer obliging Diane de Poitiers to return Chenonceau to the Crown was confirmed at Château de Chinon on May 10. Her rival Catherine de Médicis forced the former favorite of Henri II to accept the Château de Chaumont-sur-Loire in exchange.

1564
- The deed of February 25 ordered Diane de Poitiers to return Cheverny to Jacques and Philippe Hurault for 35,000 livres. Henri II's mistress had purchased the château thirteen years earlier, when Marie de Beaune's children were still minors. The sale was finally annulled after a court case.

1588
- On the orders of Henri III, the Duc de Guise was assassinated on the morning of December 23 in the king's own room at the royal château in Blois. Seeing the nearly 2-metre-long body of his enemy lying at his feet, Henri III is said to have exclaimed, "He looks bigger dead than alive!" Henri de Guise's death led indirectly to the king's assassination on August 2, 1589.

1602
- Without warning, Count Hurault returned to Cheverny in the early hours of January 26 and surprised a page escaping from his wife's room. He kills him with his sword, leaving his wife to choose between suffering the same fate or taking poison. After she had killed herself, it was discovered that the unfaithful wife was pregnant. Henri IV learned of this and condemned the Count to remain on his lands at Cheverny.

1939
- As the Second World War broke out, the Mona Lisa, along with some fifty other exceptional paintings, was exfiltrated from the Louvre Museum on August 28 for storage at Chambord. The first convoy, followed by many others, sheltered 3,690 works, which were gradually repatriated to Paris at the end of the war.

1942
- Archaeological excavations in the Romanesque crypts of Nivelles and the Abbey of Saint-Martin in Tournai inspired the cartoonist Hergé to create his album The Secret of the Unicorn, in which Tintin is trapped in vast underground passages. In the following adventure, Le Trésor de Rackham le Rouge, we discover the famous Château de Moulinsart, a replica of Cheverny with its wings removed.
